guanidinium chloride
nounUK /ˌɡwænɪˈdɪniəm ˈklɔːraɪd/
US /ˌɡwænɪˈdɪniəm ˈklɔːraɪd/
A white salt made of tiny charged pieces that scientists use to help study and unfold proteins.
The scientist added guanidinium chloride to the solution to unfold the protein.
RELATED WORDS
OTHER MEANINGS
2. A chemical reagent used to break down the shape of proteins in laboratory experiments.
Guanidinium chloride is a common reagent for denaturing enzymes.
3. A chaotropic salt that weakens the bonds holding large molecules together in water.
Adding guanidinium chloride disrupted the hydrogen bonds in the sample.
4. A compound used in molecular biology to help extract and purify nucleic acids.
The protocol uses guanidinium chloride to separate RNA from other cell parts.