greatestunease

noun
UK /ˈɡreɪtɪst ʌnˈiːz/
US /ˈɡreɪtɪst ʌnˈiːz/

The biggest feeling of being worried or not comfortable.

The strange noise in the dark house gave her the greatestunease.


OTHER MEANINGS

2. The most serious feeling that something is wrong.

He felt the greatestunease about the test results.

3. The strongest sense of awkwardness in a situation.

Walking into the silent room caused him the greatestunease.

4. The peak level of mild sickness or bother.

The bumpy ride brought her the greatestunease.