anguish
nounUK /ˈæŋ.ɡwɪʃ/
US /ˈæŋ.ɡwɪʃ/
A very strong feeling of sadness or pain.
She cried out in anguish when she lost her favorite toy.
OTHER MEANINGS
2. Great physical pain or suffering.
He felt anguish in his injured leg.
3. To feel or cause great emotional pain.
The memory of the accident anguished her for years.
4. Extreme worry or anxiety about something.
The parents waited in anguish for news of their child.